![]() ![]() Recently, there is increasing evidence that the acute phase inflammatory response induced by cytokines is closely related to the generation of insulin resistance and Type 2 diabetes mellitus. T2DM is considered a multifactorial disease, several hypotheses have tried to explain the origin of the pathology that is, that it is an abnormality of the anterior hypothalamus and the endocrine pancreas caused by progressive ischemia or that there is abnormal islet innervation. WHO calculates that 171 million people around the world have diabetes and that by 2030, its prevalence will reach epidemic proportions, affecting 366 million. ![]() Changes in human behavior and lifestyles in the last century have caused a great increase in prevalence of Type 2 diabetes mellitus. ![]()
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